Involvement of LEM3/ROS3 in the uptake of phosphatidylcholine with short acyl chains in Saccharomyces cerevisiae.

نویسندگان

  • Yusuke Ono
  • Ryouichi Fukuda
  • Akinori Ohta
چکیده

A Saccharomyces cerevisiae strain deficient in phosphatidylethanolamine methyltransferase that exhibits choline auxotrophy grew in the presence of dioctanoyl phosphatidylcholine (diC8PC). We isolated and characterized mutants defective in growth in the diC8PC-containing medium. Mutations in LEM3/ROS3 impaired growth in that medium, indicating that Lem3p is involved in the utilization of extracellular phosphatidylcholine (PC) with short acyl chains.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 73 3  شماره 

صفحات  -

تاریخ انتشار 2009